Judith S. Sebolt: search on Z-Library

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1

10.1038/10533

Sebolt-Leopold, Judith S., Dudley, David T., Herrera, Roman, Becelaere, Keri Van, Wiland, Amy, Gowan, Richard C., Tecle, Haile, Barrett, Stephen D., Bridges, Alexander, Przybranowski, Sally, Leopold,

Journal:

Nature Medicine

Year:

1999

Language:

english

File:

PDF, 386 KB

english, 1999

2

Development of anticancer drugs targeting the MAP kinase pathway

Sebolt-Leopold, Judith S

Journal:

Year:

2000

Language:

english

File:

PDF, 197 KB

english, 2000

3

Targeting MEK is Effective Chemoprevention of Hepatocellular Carcinoma in TGF-α-Transgenic Mice

Sabrina C. Wentz, Huangbing Wu, Michele T. Yip-Schneider, Matthew Hennig, Patrick J. Klein, Judith Sebolt-Leopold, C. Max Schmidt

Journal:

Journal of Gastrointestinal Surgery

Year:

2008

Language:

english

File:

PDF, 175 KB

english, 2008

4

Enhancement of alkylating agent activity in vitro by PD 128763, a potent poly(ADP-ribose) synthetase inhibitor

Judith S. Sebolt-Leopold, Sylvia V. Scavone

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1992

Language:

english

File:

PDF, 358 KB

english, 1992

5

CI-1040 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK)

Lee F Allen, Judith Sebolt-Leopold, Mark B Meyer

Journal:

Seminars in Oncology

Year:

2003

Language:

english

File:

PDF, 764 KB

english, 2003

6

Unraveling the complexities of the Raf/MAP kinase pathway for pharmacological intervention

Roman Herrera, Judith S. Sebolt-Leopold

Journal:

Trends in Molecular Medicine

Year:

2002

Language:

english

File:

PDF, 244 KB

english, 2002

7

Comparative molecular field analysis of in vitro growth inhibition of L1210 and HCT-8 cells by some pyrazoloacridines

Horwitz, Jerome P., Massova, Irina, Wiese, Thomas E., Wozniak, Antoinette J., Corbett, Thomas H., Sebolt-Leopold, Judith S., Capps, David B., Leopold, Wilbur R.

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 1.96 MB

english, 1993

8

MAPK Signaling Is Required for Dedifferentiation of Acinar Cells and Development of Pancreatic Intraepithelial Neoplasia in Mice

Collins, Meredith A., Yan, Wei, Sebolt–Leopold, Judith S., Pasca di Magliano, Marina

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 16.55 MB

english, 2014

9

A Role for K-ras in Conferring Resistance to the MEK Inhibitor, CI-1040

Wangab, Yuli, Van Becelaere, Keri, Jiang, Ping, Przybranowski, Sally, Omer, Charles, Sebolt-Leopold, Judith

Journal:

Year:

2005

Language:

english

File:

PDF, 972 KB

english, 2005

10

Synthesis and evaluation of a series of 3,5-disubstituted benzisoxazole-4,7-diones. Potent radiosensitizers in vitro

Suto, Mark J., Stier, Michael A., Winters, R. Thomas, Turner, William R., Pinter, Cheryl D., Elliott, William E., Sebolt-Leopold, Judith S.

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 621 KB

english, 1991

11

Protein prenylation: from discovery to prospects for cancer treatment

Michael H Gelb, Jeffrey D Scholten, Judith S Sebolt-Leopold

Journal:

Current Opinion in Chemical Biology

Year:

1998

Language:

english

File:

PDF, 1.02 MB

english, 1998

12

Effects of PD 128763, a New Potent Inhibitor of Poly(ADP-Ribose) Polymerase, on X-Ray-Induced Cellular Recovery Processes in Chinese Hamster V79 Cells

Carla M. Arundel-Suto, Sylvia V. Scavone, William R. Turner, Mark J. Suto and Judith S. Sebolt-Leopold

Journal:

Radiation Research

Year:

1991

Language:

english

File:

PDF, 918 KB

english, 1991

13

Inhibitors of Bcr-abl... breaking new ground again

Ohren, Jeffrey F, Sebolt-Leopold, Judith S

Journal:

Nature Chemical Biology

Year:

2006

Language:

english

File:

PDF, 185 KB

english, 2006

14

Targeting the mitogen-activated protein kinase cascade to treat cancer

Sebolt-Leopold, Judith S., Herrera, Roman

Journal:

Nature Reviews Cancer

Year:

2004

Language:

english

File:

PDF, 246 KB

english, 2004

15

Structure−Activity Relationships of Cysteine-Lacking Pentapeptide Derivatives That Inhibit ras Farnesyltransferase

Leonard, Daniele M., Shuler, Kevon R., Poulter, Cynthia J., Eaton, Scott R., Sawyer, Tomi K., Hodges, John C., Su, Ti-Zhi, Scholten, Jeffrey D., Gowan, Richard C., Sebolt-Leopold, Judith S., Doherty,

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 195 KB

english, 1997

16

Novel limonene phosphonate and farnesyl diphosphate analogues: design, synthesis, and evaluation as potential protein-farnesyl transferase inhibitors

Jeffrey T Eummer, Barbara S Gibbs, Todd J Zahn, Judith S Sebolt-Leopold, Richard A Gibbs

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 303 KB

english, 1999

17

Multi-enzyme-targeted chemotherapy by acivicin and actinomycin

George Weber, Noemi Prajda, May S. Lui, Joan E. Denton, Takashi Aoki, Judith Sebolt, Yong-Su Zhen, M.E. Burt, Mary A. Faderan, Melissa A. Reardon

Journal:

Advances in Enzyme Regulation

Year:

1982

Language:

english

File:

PDF, 962 KB

english, 1982

18

Rapid in vivo inactivation by acivicin of CTP synthetase, carbamoyl-phosphate synthetase II, and amidophosphoribosyltransferase in hepatoma

Joan E. Denton, May S. Lui, Takashi Aoki, Judith Sebolt, George Weber

Journal:

Year:

1982

Language:

english

File:

PDF, 449 KB

english, 1982

19

DCE and DW-MRI monitoring of vascular disruption following VEGF-Trap treatment of a rat glioma model

Benjamin A. Hoff, Mahaveer S. Bhojani, John Rudge, Thomas L. Chenevert, Charles R. Meyer, Stefanie Galbán, Timothy D. Johnson, Judith Sebolt Leopold, Alnawaz Rehemtulla, Brian D. Ross, Craig J. Galbán

Journal:

NMR in Biomedicine

Year:

2012

Language:

english

File:

PDF, 367 KB

english, 2012

20

Pancreatic Cancer Cell Genetics and Signaling Response to Treatment Correlate with Efficacy of Gemcitabine-Based Molecular Targeting Strategies

Bryan Holcomb, Michele T. Yip-Schneider, Jesus M. Matos, Jennifer Dixon, Jason Kennard, Julie Mahomed, Rajasubramaniam Shanmugam, Judith Sebolt-Leopold, C. Max Schmidt

Journal:

Journal of Gastrointestinal Surgery

Year:

2008

Language:

english

File:

PDF, 288 KB

english, 2008

21

Oncogenic Mutants of MEK1 : A Trilogy Unfolds

Maust, Joel D., Whitehead, Christopher E., Sebolt-Leopold, Judith S.

Journal:

Cancer Discovery

Year:

2018

Language:

english

File:

PDF, 2.69 MB

english, 2018

22

Costello and cardio-facio-cutaneous syndromes: Moving toward clinical trials in RASopathies

Katherine A. Rauen, Anuradha Banerjee, W. Robert Bishop, Jennifer O. Lauchle, Frank McCormick, Martin McMahon, Teri Melese, Pamela N. Munster, Sorena Nadaf, Roger J. Packer, Judith Sebolt-Leopold, Dav

Journal:

American Journal of Medical Genetics Part C: Seminars in Medical Genetics

Year:

2011

Language:

english

File:

PDF, 182 KB

english, 2011

23

In vivo inactivation by acivicin of carbamoylphosphate synthetase II in rat hepatoma

Takashi Aoki, Judith Sebolt, George Weber

Journal:

Biochemical Pharmacology

Year:

1982

Language:

english

File:

PDF, 685 KB

english, 1982

24

One Step at a Time â Clinical Evidence that KRAS Is Indeed Druggable

LoRusso, Patricia M., Sebolt-Leopold, Judith S.

Journal:

New England Journal of Medicine

Year:

2020

File:

PDF, 343 KB

2020

25

A new class of analog of the bifunctional radiosensitizer .alpha.-(1-aziridinylmethyl)-2-nitro-1H-imidazole-1-ethanol (RSU 1069): the cycloalkylaziridines

Suto, Mark J., Stier, Michael A., Werbel, Leslie M., Arundel-Suto, Carla M., Leopold, Wilbur R., Elliott, William E., Sebolt-Leopold, Judith S.

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 716 KB

english, 1991

26

Development of Preclinical Models to Understand and Treat Colorectal Cancer

Sebolt-Leopold, Judith

Journal:

Clinics in Colon and Rectal Surgery

Year:

2018

Language:

english

File:

PDF, 98 KB

english, 2018

27

Activity of the pyrazoloacridines against multidrug-resistant tumor cells

Judith Sebolt, Martha Havlick, Katherine Hamelehle, James Nelson, Wilbur Leopold, Robert Jackson

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1989

Language:

english

File:

PDF, 608 KB

english, 1989

28

Novel Farnesol and Geranylgeraniol Analogues: A Potential New Class of Anticancer Agents Directed against Protein Prenylation

Gibbs, Barbara S., Zahn, Todd J., Mu, YongQi, Sebolt-Leopold, Judith S., Gibbs, Richard A.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 193 KB

english, 1999

29

Cyclooxygenase-2 Influences Response to Co-Targeting of MEK and CDK4/6 in a Subpopulation of Pancreatic Cancers

Maust, Joel D, Frankowski-McGregor, Christy L, Bankhead, Armand, Simeone, Diane M., Sebolt-Leopold, Judith S

Journal:

Molecular Cancer Therapeutics

Year:

2018

Language:

english

File:

PDF, 3.67 MB

english, 2018

30

The Effects of a Novel MEK Inhibitor PD184161 on MEK-ERK Signaling and Growth in Human Liver Cancer

Klein, Patrick J., Schmidt, C. Max, Wiesenauer, Chad A., Choi, Jennifer N., Gage, Earl A., Yip-Schneider, Michele T., Wiebke, Eric A., Wang, Yufang, Omer, Charles, Sebolt-Leopold, Judith S.

Journal:

Year:

2006

Language:

english

File:

PDF, 213 KB

english, 2006

31

Feline Focus

Klein, Patrick J., Schmidt, C. Max, Wiesenauer, Chad A., Choi, Jennifer N., Gage, Earl A., Yip-Schneider, Michele T., Wiebke, Eric A., Wang, Yufang, Omer, Charles, Sebolt-Leopold, Judith S.

Journal:

Journal of Feline Medicine & Surgery

Year:

2009

Language:

english

File:

PDF, 4.19 MB

english, 2009

32

Negative correlation of L-glutamine concentration with proliferation rate in rat hepatomas

Judith S. Sebolt, George Weber

Journal:

Year:

1984

Language:

english

File:

PDF, 326 KB

english, 1984

33

Inhibitors of farnesyl:protein transferase—A possible cancer chemotherapeutic

Jeffrey D. Scholten, Karen Zimmerman, Maritza Oxender, Judith Sebolt-Leopold, Richard Gowan, Daniele Leonard, Donald J. Hupe

Journal:

Bioorganic & Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 473 KB

english, 1996

34

Non-Peptidic Prenyltransferase Inhibitors: Diverse Structural Classes and Surprising Anti-Cancer Mechanisms

Gibbs, Richard, Zahn, Todd, Sebolt-Leopold, Judith

Journal:

Current Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 213 KB

english, 2001

35

Inactivation by acivicin of carbamoyl-phosphate synthetase II of human colon carcinoma

Judith S. Sebolt, Takashi Aoki, John N. Eble, John L Glover, George Weber

Journal:

Biochemical Pharmacology

Year:

1985

Language:

english

File:

PDF, 383 KB

english, 1985

36

Dual inhibition of allosteric mitogen-activated protein kinase (MEK) and phosphatidylinositol 3-kinase (PI3K) oncogenic targets with a bifunctional inhibitor

Van Dort, Marcian E., Galbán, Stefanie, Wang, Hanxiao, Sebolt-Leopold, Judith, Whitehead, Christopher, Hong, Hao, Rehemtulla, Alnawaz, Ross, Brian D.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 2.00 MB

english, 2015

37

In vivo and in vitro anticancer activity of the structurally novel and highly potent antibiotic CI-940 and its hydroxy analog (PD 114,721)

Billy J. Roberts, Katherine L. Hamelehle, Judith S. Sebolt, Wilbur R. Leopold

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1986

Language:

english

File:

PDF, 556 KB

english, 1986

38

Mechanisms of drug inhibition of signalling molecules

Sebolt-Leopold, Judith S., English, Jessie M.

Journal:

Year:

2006

Language:

english

File:

PDF, 427 KB

english, 2006

39

Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon

Haigis, Kevin M, Kendall, Krystle R, Wang, Yufang, Cheung, Ann, Haigis, Marcia C, Glickman, Jonathan N, Niwa-Kawakita, Michiko, Sweet-Cordero, Alejandro, Sebolt-Leopold, Judith, Shannon, Kevin M

Journal:

Nature Genetics

Year:

2008

Language:

english

File:

PDF, 922 KB

english, 2008

40

The Pyrazoloacridines: Approaches to the Development of a Carcinoma-Selective Cytotoxic Agent

Jackson, Robert C., Sebolt, Judith S., Shillis, Joan L., Leopold, Wilbur R.

Journal:

Cancer Investigation

Year:

1990

Language:

english

File:

PDF, 809 KB

english, 1990

41

Knockdown of Chk1, Wee1 and Myt1 by RNA Interference Abrogates G2 Checkpoint and Induces Apoptosis

Wang, Yuli, Decker, Stuart J., Sebolt-Leopold, Judith

Journal:

Cancer Biology & Therapy

Year:

2004

Language:

english

File:

PDF, 972 KB

english, 2004

42

Deciphering the Complexity of MEK Mutations in the Clinic

Whitehead, Christopher E., Sebolt-Leopold, Judith S.

Journal:

Cancer Research

Year:

2020

File:

PDF, 213 KB

2020

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